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About DigiFab®

DigiFab® Digoxin Immune Fab (Ovine) is a sterile, purified, lyophilized preparation of digoxin-immune ovine Fab (monovalent) immunoglobulin fragments.1

Each vial of DigiFab® Digoxin Immune Fab (Ovine), which will bind approximately 0.5 mg digoxin, contains 40 mg of digoxin immune Fab, 75 mg (approx) of mannitol USP, and 2 mg (approx) sodium acetate USP as a buffering agent.1

The product contains no preservatives and is intended for intravenous administration after reconstitution with 4 mL of Sterile Water for Injection USP.1

DigiFab® Digoxin Immune Fab (Ovine)1:

  • Rapidly binds to and neutralizes digoxin with measurable results
    • Rapidly reduces levels of free digoxin to undetectable2
    • More than 40% of digoxin excreted by 24 hours
    • 93% of patients resolved their digoxin poisoning by 20 hours
Read about how DigiFab® is produced »
Read about mechanism of action of DigiFab® »
Read about the efficacy and risks of DigiFab® »


  1. DigiFab® [prescribing information]. BTG International Inc. January 2012.
  2. Ward SB, Sjostrom L, Ujhelyi MR. Comparison of the Pharmacokinetics and In Vivo Bioaffinity of DigiTAb Versus Digibind. Ther Drug Monit 2000;22(5):599-607.

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