digoxin immune fab digifab logo DIGIFab

DIGIFab® Manufacturing Process1,2

Quality Assurance Through a Proven, Time-Intensive, 

and Complex Process


Immunogens consisting of an analogue of digoxin are produced in a laboratory and used to immunise sheep


The immune system recognises these antigens as foreign and produces antibodies


The antibodies are then collected, separated, purified, and formulated into DIGIFab®


  1. Data on file. BTG International Ltd.
  2. Maes K, Depudyt P, Vermassen J, et al. Foxglove poisoning: diagnostic and therapeutic differences with medicinal digitalis glycosides overdose. Acta Clinica Belgica. 2022;77(1):101-107